Trust Your Gut to Culturelle Culturelle® Abdominal Support and Comfort Packets relieve the intensity and reduce the frequency of severe digestive symptoms associated with all types of Irritable Bowel Syndrome (IBS) including abdominal pain bloating constipation and diarrhea. Using ingredients that work naturally with your body to make real changes these single-serve packets go beyond symptom relief and target the source of your digestive issues with the help of bioactive prebiotics found in human milk oligosaccharides (HMOs) which are unique prebiotics naturally found in breastmilk that selectively nourish and stimulate the growth of good bacteria and support your body s intestinal barrier.