Compare to the active ingredients in Monistat 3. Miconazole Nitrate Vaginal Cream (4%) is a 3-day yeast infection treatment that cures most vaginal yeast infections and relieves irritation associated with a vaginal yeast infection. Includes 3 applicators and cream. If you’re not satisfied with any Target Owned Brand item, return it within one year with a receipt for an exchange or a refund.